Steroids and derivatives
Medchemexpress LLC Resolvin D2 | 810668-37-2 | 99.9% | 376.49 | 25 UG
Resolvin D2 is a metabolite derived from docosahexaenoic acid (DHA) that exhibits anti-inflammatory and anti-infective properties. It acts as a potent regulator of leukocytes and is effective in controlling microbial sepsis. This compound also functions as a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons.
- Anti-inflammatory activities
- Anti-infective activities
- Leukocyte regulation
- Control of microbial sepsis
- TRPV1 and TRPA1 inhibition
- Resolution of inflammation and tissue regeneration
- Decreases leukocyte:endothelial interactions
- Inhibits inflammatory pain
Medchemexpress LLC Eldecalcitol | 104121-92-8 | 99.9% | C30H50O5 | 5 MG
Eldecalcitol (ED-71) is an orally active vitamin D3 analogue that inhibits bone resorption and increases bone mineral density. It also exhibits an anti-tumor effect, inhibits cell proliferation, migration, and induces apoptosis by suppressing GPx-1.
- Orally active vitamin D3 analogue
- Inhibits bone resorption and increases bone mineral density
- Exhibits anti-tumor effects
- Inhibits cell proliferation and migration
- Induces apoptosis by suppressing GPx-1
- Shows no cytotoxicity at 0-50 nM for 24 hours
- Reduces cell death induced by LPS
- Inhibits LPS-induced pyroptosis by activating Nrf2 and its effector molecule HO-1
- Arrests cell cycle at G0/G1 phase
- Stimulates focal bone formation and suppresses bone resorption
Medchemexpress LLC Cyclin D3/CCND3 Antibody (YA484) | Protein A affinity purified | 33 kDa | 10 UL
Cyclin D3/CCND3 Antibody (YA484) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Cyclin D3/CCND3. This antibody is supplied in 1*TBS (pH 7.4) containing 0.05% BSA and 40% Glycerol, with 0.05% Sodium Azide as a preservative. It is suitable for applications such as Western Blot (WB) and Immunocytochemistry/Immunofluorescence (ICC/IF).
- Host: Rabbit
- Reactivity: Human, Mouse
- Clonality: Monoclonal antibody
- Purity: Protein A affinity purified
- Formulation: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% Sodium Azide
- Storage: Stored at -20°C for 1 year; avoid repeated freeze/thaw cycles
- Application: WB (1:500-1:1000)
- Application: ICC/IF (1:50-1:100)
- Background: Functions as a regulatory component of the cyclin D3-CDK4 complex, regulating cell cycle during G(1)/S transition by phosphorylating and inhibiting retinoblastoma protein family members.
Cayman Chemical 5 6-trns-VItamIn D3 5mg
An isomer of vitamin D3; increases tibia ash weight and bone mineralization in vitamin D-deficient chicks at 1, 3, and 10 UG/day; induces intestinal calcium transport and bone calcium mobilization in anephric rats fed a low-calcium and vitamin D-deficient diet at 25 UG/animal
Medchemexpress LLC Vitamin D3 (Standard) | 67-97-0 | C27H44O | 50 MG
Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occurring form of vitamin D and serves as an analytical standard. This product is intended for research and analytical applications, inducing cell differentiation and preventing the proliferation of cancer cells.
- Analytical standard for Vitamin D3
- Intended for research and analytical applications
- Induces cell differentiation and prevents proliferation of cancer cells
- Commonly used in qualitative, quantitative, and methodological research
- Suitable for HPLC, GC, and MS applications
- Naturally occurring form of vitamin D
Medchemexpress LLC Ranolazine-d3 | 1054624-77-9 | 99.5% | 25 MG
Ranolazine-d3 is the deuterium labeled version of Ranolazine, an anti-angina agent that inhibits the late phase of inward sodium current (INa) and IKr, with IC50 values of 6 μM and 12 μM, respectively, without impacting heart rate or blood pressure. It also acts as a partial fatty acid oxidation (FAO) inhibitor. This compound is an antianginal agent primarily used for research purposes. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Selleck Chemical LLC Vitamin A Acetate S4083-50mg
Vitamin A Acetate (Retinyl Retinol) is a group of unsaturated nutritional hydrocarbons that includes retinol retinal retinoic acid and several provitamin A carotenoids among which beta-carotene is the most important
Medchemexpress LLC HY-15267B 1mg Medchemexpress, (24S)-MC 976 CAS:112849-14-6 Purity:>98%
Medchemexpress, HY-15267B 1mg (24S)-MC 976 CAS:112849-14-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cambridge Isotope Laboratories 2 6-Dinitrotoluene (methyl-D3 98%) 1 mg/mL in acetonitrile 1 mL
2 6-Dinitrotoluene (methyl-D3 98%) 1 mg/mL in acetonitrile 1 mL
Cambridge Isotope Laboratories 1 25-Dihydroxyvitamin D2 (unlabeled) CP 95% 1 mg
1 25-Dihydroxyvitamin D2 (unlabeled) CP 95% 1 mg
MOLECULAR DEPOT LLC 25-OH Vitamin D3 Biotin - 1 mg
25-OH Vitamin D3 Biotin Conjugate consists of 25-OH Vitamin D3 conjugated to Biotin via a 22 A spacer arm The spacer adds flexibility to the 25-OH Vitamin D3 moiety which is required for its interaction with specific antibodies and other binding partners This compound has been tested for use in several 25-OH Vitamin D applications including ELISA The conjugate is supplied as a DMSO stock solution For in vitro research use only
Medchemexpress LLC Fluorometholone acetate | 3801-06-7 | 98.5% | 50MG
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It potently inhibits carbonic anhydrase (CA) with IC50s of 2.18 μM and 17.5 μM for hCA-I and hCA-II, respectively. Fluorometholone acetate has an anti-inflammatory effect and has the potential for external ocular inflammation research.
- Synthetic glucocorticoid corticosteroid
- Potent carbonic anhydrase inhibitor
- Exhibits anti-inflammatory effects
- Potential for external ocular inflammation research
Medchemexpress LLC Fluorometholone acetate | 3801-06-7 | 98.5% | 100 MG
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is a potent inhibitor of carbonic anhydrase (CA) with IC50 values of 2.18 μM for hCA-I and 17.5 μM for hCA-II. It also has an anti-inflammatory effect and has potential for research into external ocular inflammation.
- Synthetic glucocorticoid corticosteroid
- Corticosteroid ester
- Potent inhibitor of carbonic anhydrase (CA)
- Anti-inflammatory effect
- Potential for external ocular inflammation research
- For research use only
Medchemexpress LLC Fluorometholone | 426-13-1 | 99.4% | 50 MG
Fluorometholone is a synthetic glucocorticoid and a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic properties. It can be used for the research of dry eye. This product is for research use only and not sold to patients.
- Synthetic glucocorticoid
- Glucocorticoid receptor agonist
- Possesses anti-inflammatory and anti-allergic properties
- Can be used for the research of dry eye
- Increases the gene expression of MUC1, MUC4, MUC16 and MUC19 in conjunctival and corneal epithelial cells through activation of glucocorticoid receptors